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العنوان
Comparative Antidiabetic Effect of White, Black and Sprouted Garlic Using Male Albino Rats /
المؤلف
Merika, Eslam Al-Amir Abd-Elrahman.
هيئة الاعداد
مشرف / إسلام الأمير عبدالرحمن مريقة
مشرف / محمد سميرالدشلوطي
مناقش / شريف صبرى رجب
مناقش / عيد على زكي
الموضوع
nutrition.
تاريخ النشر
2019.
عدد الصفحات
157 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
اقتصاد منزلي
تاريخ الإجازة
2/5/2019
مكان الإجازة
جامعة المنوفية - كلية الإقتصاد المنزلى - قسم التغذية
الفهرس
Only 14 pages are availabe for public view

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Abstract

The main target of the present investigation was to study the effect
of white, black, and sprouted garlic (5%) as treatment and protection on
the diabetes mellitus albino rats. Thirty two male albino divided into three
main groups. The first group (4 rats) fed on basal diet as a (control groupve),
while in the second main group (16 rats) diabetes mellitus was induced
in normal healthy albino rats by intraperitoneal injection of alloxano 150
mg/kg body weight at the beginning of the experimental period. The second
main group divided into four groups (4 rats each). Groups (1) fed on basal
diet (control positive group +ve). Groups (3-5) (treatment groups) fed on
basal diet containing 5% white, black and sprouted garlic respectively. For
the third main group (12 rats) diabetes mellitus was induced in normal
healthy albino rats by intraperitoneal injection of alloxano 150 mg/kg body
weight on the 26th day of the experimental period. The third main group
divided into three groups (4 rats each). Groups (6-8) (protection groups)
fed on basal diet containing 5% white, black and sprouted garlic
respectively. At the end of the experimental period (28 days) rats were
fasted over night before sacrificing, blood was collected then centrifuged
to separate the serum. Liver, kidneys, lungs, heart and spleen removed from
each rat, cleaned and weighted to estimate of organs weight. The obtained
results revealed that, treatment by alloxan led to significant increase in
serum glucose, cholesterol, triglycerides, LDL, VLDL, uric acid, urea,
creatinine, AST, ALT and ALP, and decreased HDL. Treating rats which
were injected by alloxan with the levels from white, black and sprouted
garlic (5%) showed decreased levels of serum glucose, kidney function,
liver function, LDL & VLDL, and increased serum HDL. Also improved
the other parameters including internal organs weights.
Key words: Diabetes mellitus, Glucose, Kidney function, Liver
function, Lipid profile.
ABSTRAC