الفهرس 
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Abstract
Respiratory distress syndrome (RDS) is one of the most common respiratory complications of prematurity. Its incidence is inversely related to gestational age and birth weight. It occurs in 60-80% of infants <28wk of gestational age, in 15-30% those between 32 and 36wk of gestational age, and rarely in those >37wk of gestational age
A variety of hormones including glucocorticoids and thyroid hormones are considered to influence pulmonary development and lung surfactant production. Glucocorticoids can interact synergistically with other factors such as thyroid hormones and prolactin to promote early lung maturation. Several clinical studies have confirmed that pregnant women at risk of preterm delivery benefit from a combined treatment of thyroid releasing hormone TRH and glucocorticoids.
The aim of this study is to study the level of serum free tetra- iodothyronine (FT4) and Thyroid stimulating hormone (TSH) in cases of respiratory distress syndrome (RDS) in preterm neonates and it’s correlation with other clinical findings.
This study was done on 60 preterm neonates suffering from RDS and 30 healthy controls. Informed consent obtained from the parents of all cases after full explanation of benefits and risks.
All subjects was evaluated as follows:
1) Full history taking.
2) Clinical examination including:
Confirmation of neonate estimated gestational age.