الفهرس 
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Abstract
Summary
This study was carried out on a total of 50 females with FM and 50 healthy, age and sex matched volunteers. The patients and controls were included only if they were between 20-40 Y, married, premenopausal ,uncircumcised and sexually active during the past 6 months, able to read and give consent. Patients were recruited from females attending the Rheumatology outpatient clinic and attending gynecology and obstetrics outpatient clinic of Beni-Suef university Hospital, who met the 2010 ACR classification criteria for FM (Wolfe et al., 1990).
To evaluate the rate of SD among uncircumcised women with fibromyalgia and to assess the possible association between SD with disease activity, physical impairment and psychological status. The participants filled out anonymous self-administered Questionnaire including socio-demographic data form , the validated Arabic Female Sexual Function Index (ArFSFI) and the Arabic version of Hospital anxiety and depression scale (HADS-A)(HADS-D).Fibromyalgia impact questionnaire (FIQ),and Visual analog scale (VAS), were completed by fibromyalgia patients group only. Fibromyalgia patients only were examined for tender point count (TPC). Male partner of all participants were interviewed to answer International index of erectile function-5 (IIEF-5).
After statistical analysis, the results were as follows:
Both groups were comparable in terms of socio-demographic and clinical characteristics as well as anthropometric measures.
- There was highly significant difference between the two groups regarding the total as well as individual domain scores, with lower scores among patients.
68% of patients and 16% of controls reported abnormal SF according to the FSFI total scores. Moreover, patients showed higher frequency of abnormality related to lubrication (84%), orgasm (80%), pain (88%), satisfaction (82%), arousal (84%), and desire (62%) domains. The difference between the two group was highly significant.
The mean scores of both anxiety and depression subscales of HADS were significantly higher among patients when compared with controls.
Higher percentages of patients with FM reported possible or probable psychological morbidity on HADS-A and HADS-D subscales, while the majority of controls reported normal levels of psychological wellbeing. The difference between the two groups was highly significant.
IIEF-5 scores were significantly higher among healthy controls compared with patients with fibromyalgia.
Additionally mild and moderate erectile dysfunction (ED) was respectively encountered in (38%) and (26%) of patients with fibromyalgia, However, only (16%) of healthy controls exhibited mild degree of ED. In other words, impairment of erectile function was significantly higher among patients’ group.
Non-significant correlations were detected between FFSI total scores and the following clinical parameters female age, duration of marriage, number of children, BMI as well as age of male partner. Similarly, these clinical parameters were insignificantly associated with each of FSFI individual domain scores, TPC, pain severity on VAS, FIQ scores, anxiety and depression subscales of HADS (HADS-A and HADS-D), as well as IIEF-5 scores.
Highly significant positive correlations were found between IIEF-5 scores and FSFI total as well as domain scores.
Highly significant positive correlations were found between frequency of intercourse per week and FSFI total and domain scores as well as IIEF-5 scores.
Highly significant positive correlations were found between duration of disease and TPC, VAS, FIQ, as well as anxiety and depression subscales of HADS (HADS-A and HADS-D).
Highly significant negative correlations were found between duration of disease and FSFI total and domain scores as well as IIEF-5 scores.
TPC, VAS, FIQ as well as HADS (HADS-A - HADS-D) showed highly negative association with each of frequency of intercourse and IIEF-5 scores.
Highly significant negative correlations were noticed between FSFI total as well as domain scores and TPC, VAS, FIQ and HADS (HADS-A and HADS-D).
Highly significant positive correlations were found between anxiety and depression subscales of HADS and TPC, VAS as well as FIQ.
Highly significant positive correlations were found between VAS and TPC.
Highly significant positive correlations were found between TPC and FIQ.
Highly significant positive correlations were found between FIQ and VAS.
Highly significant positive correlations were found between HADS-A and HADS-D subscales.
Linear regression analysis was done and showed High statistical significance was found between FSFI overall scores and anxiety; pain severity; and frequency of intercourse per week.