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Abstract Introduction: Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass and function (strength and power) with a risk of adverse outcomes such as physical disability, poor quality of life and death. •Aim of the work: The aim of our study was to assess muscle status and sarcopenia among patients with liver cirrhosis and its relation to patient physical activity and dietary history as well as liver disease progression. •Patient and methods: This was a cross-sectional study conducted on 150 patients underwent through clinical evaluation (History, complete physical examination). Laboratory tests including: CBC, serum creatinine, liver function tests, serum CPK and serum calcium. Assessment of muscle status was done by anthropometric parameters (MAMC&TSF) and grip strength. Also, questionnaire for assessment of nutritional status and physical activity. The patients were divided into two groups based on the presence or absence of sarcopenia then we compared patient characteristics. •Results: Of included participants (53.3% n=80) patients were diagnosed with sarcopenia, (66.4%) were men versus (33.6%) were women. The sarcopenic patients were older than non sarcopenic one and had lower BMI. Majority of patients with sarcopenia consumed diet with low protein, low vitamin and iron. Assessment of physical activity by IPAQ demonstrated more than half of sarcopenic group (53%) exerted low or no exercise. Complication of cirrhosis as ascites and hepatic encephalopathy were more prevalent among sarcopenic patients. •Conclusion: The prevalence of sarcopenia was highest in cirrhotic patients with older age, low BMI and low protein intake. Also, the worse the condition of the liver the greater the degree of muscle weakness was detected. |