الفهرس 
ACURATE NEOOnly 14 pages are availabe for public view
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Abstract
With the new development of percutaneous intervention for heart valves,it opened the door for a high-risk group of patients with an alternative to risky surgical intervention for such a high-risk group, these interventions include both the valve repair as in case of MitraClip or the CardioBand and valve replacement as in the case of transcatheter aortic valve replacement.Our study aimed to study the consequences and outcome of percutaneous Intervention on cardiac valves. Our study was conducted at the epartment of cardiovascular medicine at the catholic university of the sacred eart, Rome, Italy.We designed a cohort perspective study that included all patients went for rcutaneous intervention for heart valves during the study period, all atients were subjected to routine history taking and lab investigation together with surgical risk score calculation and through discussion during the heart team meeting before intervention.After intervention, all patients were re-evaluated to assess both the clinical improvement together with the effect of the intervention on the heart valve.Our study included 183 patients during 2 years, was divided into two groups according to the type of intervention, the first group included 144 patients and all were subjected to TAVR with an average age of 82 years and a high surgical risk score (average STS score was 8.4 ± 4.5) procedural success was achieved in 99.3% of patients with only one patient that had an embolized valve in the ascending aorta. The most frequent complication occurred was the conduction defect (30.6%) followed by major vascular complication (8.5%) a 118 subgroup analysis of the transfemoral TAVR was conducted to predict the incidence of vascular complication and it was found that pre-TAVR MLD and history of peripheral arterial disease had a significant association with vascular complications.