الفهرس 
Definition & Classification & Risk factorsOnly 14 pages are availabe for public view
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Abstract
This study aims to assess whether uterine artery Doppler indices can predict significant causes of uterine bleeding in patients with perimenopausal bleeding or not.
This prospective observational study was conducted on 106 women with perimenopausal bleeding [who were subdivided into two groups, one with non-significant causes (52 patients) and the other with significant causes (54 patients)] and 50 healthy controls with transvaginal ultrasonic colour Doppler study performed prior to endometrial sampling by D&C in those with perimenopausal bleeding. Test characteristics of uterine artery pulsatility index (PI) and resistance index (RI) for prediction of significant causes of bleeding was the main outcome measure.
Uterine artery PI at cut-off value of 1.82 with AUC of .834, sensitivity of 70.8%, specificity of 92%, PPV of 94.9%, NPV of 69.9% and accuracy of 78% while uterine artery RI at cut-off value of 0.575 with AUC of.998, sensitivity of 96.2%, specificity of 100%, PPV of 100%, NPV of 92.6% and accuracy of 97% were predictive of significant causes of perimenopausal bleeding.
Uterine artery Doppler is simple, readily-available and non-invasive tool that could be beneficial in conjunction with endometrial sampling to detect significant causes of perimenopausal bleeding.