الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 103 |  |  |
| | | from | 103 | | |
Abstract
Summary
Age related macular degeneration is the leading cause for loss of sight in elderly people in industrial countries. In Caucasian populations it affects from less than 0.5% in subjects 50 to 60 years, to 12% and 16% in men and women aged 80 years or more, respectively. Late AMD is more frequent in women than in men in the oldest age group (80 years or more). Neovascular AMD represents 55% of all late AMD cases.
FFA was considered as the gold standard procedure for diagnosis of wet AMD. With help of structural OCT in assessing degree of macular involvement and follow up with treatment. FFA is an invasive and time consuming procedure due to use of stain. Beside allergic reactions to dye, some people can’t tolerate flourescien dye as kidney impairment patients and pregnant women.
On the other side OCT present itself as a novel non-invasive rapid economic procedure to visualize retinal vasculature without dye using. It applies modern technique by applying motion and phase difference between successive B scans of new rapid 4D OCT devices.
OCT-A has limitations such as artifacts, limited field of view and non-visualization of slow blood flow areas.
In this study we are trying to compare results of both investigations together so as to know if OCT-A can replace FFA as a gold standard procedure for diagnosis of wet AMD.
We collect 30 eyes of 27 patients with wet AMD whom underwent full ophthalmological examination, OCT-A and FFA.
We found that OCT-A have great advantages over FFA regarding time consuming, requirement of dilatation, no need of dye and exact visualization of the neovessels and its site but it has some limitations mainly artifacts which can be dialed with by using a tracking system like that that used in LAISK and by improving softwares to eliminate other types of artifacts.
OCT-A as a rapid, non-invasive, technique is going to replace FFA for diagnosis of wet AMD with further developments eliminating its limitations.