الفهرس 
Introduction
Pathophysiology of bone metastasisOnly 14 pages are availabe for public view
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Abstract
Bone is one of the most common sites of distant metastasis in cancer patients. Imaging of bone metastases facilitates the assessment of the morphology and the extent of the disease. A major challenge for detection and characterization of skeletal metastases is the appropriate choice of imaging modality and technique, respectively.
Planar bone scintigraphy is highly sensitive in detecting skeletal metastatic lesions; however its specificity is low so it was necessary to search for another modality to obtain more accurate diagnosis.
In this study, the diagnostic performance of SPECT/CT bone scintigraphy was evaluated in comparison to Tc-99m MDP planar bone scintigraphy in characterization of suspicious osseous lesions in patients with known cancer.
Our results showed that SPECT/CT bone scintigraphy has better sensitivity and specificity than planar bone scintigraphy in characterization of suspicious osseous lesions by its exact anatomical localization and morphological characterization leading to accurate diagnosis and better patient management.