الفهرس 
Introduction
Pre-Eclampsia and Intrauterine Growth RestrictionOnly 14 pages are availabe for public view
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Abstract
Prenatal care aimed to improve the outcome of pregnancy in terms of perinatal morbidity and mortality by identifying women at risk of complications of uteroplacental insufficiency; pre-eclampsia and IUGR. The adverse perinatal outcomes of pre-eclampsia and eclampsia are attributed largely to preterm delivery, which occurs secondary to maternal or fetal complications, intrauterine growth restriction (IUGR) and fetal death.
Evaluation of the predicting value of combining the 3D assessment of placental volume with the assessment of placental perfusion indices through 3D power Doppler (3DPD) at the first trimester in pregnant women at high risk to develop PE could be a suitable screening method. Doppler ultrasound has been demonstrated to be a reliable, non-invasive method of examining uteroplacental perfusion. Scientific interest is now focused on early pregnancy
This study is a prospective cohort one which included 100 women at risk factor of preeclampsia as women with singleton pregnancy. This study was done in El-Minia University hospital. The objective of this study was to compare the 3D power doppler of pregnant normal women who are not at risk and studying the ability of 3D-placental volume and vascular flow indices to predict preeclampsia.
All females included in this study were divided into the two groups: pre-eclampsia group (n=22) and normal non complicated pregnancy group (n=76) and 2 cases were excluded because they had abortion. 64 cases were multigravida and 36 cases were primegravidea complaining of essential hypertension and chronic medical disorder.
Females included in this study were subjected to transabdominal Doppler ultrasonography for assessment of placental volume measurements, pulasatility index (PI) and resistivity index (RI) in both uterine arteries. And assessment of the placental volume and its vascular indices (VI,FI ,VFI).
The results revealed that Placental volume (PV), Vascularization index (VI), Flow index (FI) and Vascularization flow index (VFI) was significantly (P≤ 0.05 and 0.01) lower in Pre-eclampsia group than the normal pregnancy group.
Regarding Pulsatility index (PI) and Resistance index (RI), the results indicated that PI and RI were significantly (P≤ 0.01) higher in pre-eclampic group of women than the normal pregnancy women.
In conclusion, there was a statistically significant correlation between first-trimester uterine artery Doppler indices and the placental volume and its vascular indices in the prediction of complications of uteroplacental insufficiency. Much more studies with large number of patients must be developed to reach conclusive evidence of the significance Doppler in prediction of pre-eclampsia.