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Abstract Schiff bases are the compounds containing the azomethine group (CH=N), first prepared by the scientist Hugo Schiff in 1864 from condensation a primary amine with an active carbonyl compound, usually occurring under the acid, base of catalysis or heat. They are important compounds in the coordination chemistry, especaily in the development of complexes of imines because these compounds are potentially capable of forming stable complexes with metal ions. So much interest in imines can be explained by the fact that they are widely distributed in many pharmacological activities such as anti-malarial, anticancer, antibacterial, antifungal, anti-TB activities and industrial application. Based on the above, the main aims of this thesis are: Preparation of new bi- and tetra-dentate imine ligands from condensation of 2-aminophenol or o-phenylenediamine (amine group) with 4-(diethylamine) salicylhydide or 4-(dimethylamine) benzyldehyde or 4-chlorobenzaldehyde (carbonyl group). Preparation of new Ag(I), Cu(II) and Pd (II) complexes that may have biological, catalytic activity and can bind with CT-DNA. The ligands used in the study are: • Ligand 1: CBAP 2-[(4-Chloro-benzyliden. |