الفهرس 
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Abstract
A total of 256 fish (141 freshwater and 115 marine water fish) and 175 human samples (146 stools and 29 hand swabs) were collected from Damietta governorate. All samples were submitted for bacteriological, molecular and serological examinations. PCR results showed that the prevalence of Salmonella colonization in fish was 8.59% on the other hand, in humans 11 out of 146 (7.53%) stool samples were positive, while, all of th examinated hand swabs were negative for Salmonilla. The recovered Salmonella serotypes of fish were S. Enteritides, S Heideberg, S. Virchow, S.Derby, S. Infantis, S Paratyphi A, S.Anatum, S.Typhimurim and S.Rissen. in humans, 6 Salmonilla serotypes; S. Enteritides, S.Rissen, S.Typhimurim, S.Infantis, S. larochelle and S.Anatum were identified. The current findings highlight the role of fishes as potential vectors of human salmonellosis and may indicate the high risk of zoonotic transmission of Salmonella via food chain including fishes in the investigated area.