الفهرس 
Introduction and Aim of the workOnly 14 pages are availabe for public view
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Abstract
Breast cancer is not only a leading cause of death among women but also carries a high risk of recurrence. Early detection of local recurrence can improve patients’ survival. This can be attributed by means of close clinical and imaging follow-up which is considered an important component of breast-conserving strategy.
Women with a history of breast cancer are at risk for developing local recurrences, a second ipsilat¬eral breast cancer, or contralateral breast cancer. The incidence of local recurrence is between 1 and 2% per year, with most of the recurrences occurring in the first 5 years.
Many benign changes can be noticed in the postoperative breast as {resolving edema, seroma, hematoma, fat necrosis, and abscess formation especially post chemotherapy at the operation site} all of which are expected findings. Yet recurrence is not an exception.
Thus it is mandatory to identify imaging findings that are benign or expected for short-interval imaging follow up in order to minimize unnec¬essary intervention, as well as to appropriately pick up suspicious lesions aiming for proper diagnosis and in turn management of malignant cases.
DWI is a safe, fast, noncontrast sequence that can be easily added to all MRI machines, with no significant lengthening of the examination time.
In our study we tried to assess and compare the MRI diffusion and ultrasonographic findings in postoperative breasts with breast cancer in order to differentiate between the accepted postoperative sequelae and tumor residual or recurrence.
Forty female patients were included in this prospective study. All cases underwent either CBS or MRM with or without reconstruction, at least 6 months before doing their MRI with two exceptions where the two female patients presented with pain in the early postoperative period, around 3 and 4 months. All cases were suspected for either recurrence or post-operative complication by US examination. Breast US were reviewed for all patients then followed by MRI examination. DCE-MRI was done with DWI, the b values was (0 and 750 sec/mm2). Pathology was the gold standard. Stationery or regressive course on follow up was observed in 12 cases.
Out of the 40 patients, 17 were pathologically proven as malignant lesions and 11 benign results compared to 12 patients with variable spectrum of benign postoperative changes on follow up. In our study, DWI together with conventional MRI sequences was superior to 2D-US in diagnosis of recurrent cases with 8 false positive cases and 1 false negative case while US showed 2 false negative case and 14 false positive cases. For adding more value to our study, we had assessed also the DCE-MRI for the studied group and found that DCE-MRI is superior to DWI & US in detection of tumor recurrence with only 1 false negative case and 1 false positive case.