الفهرس | Only 14 pages are availabe for public view |
Abstract Background: low birth weight (LBW) refers to term or preterm neonates with birth weight < 2500 gr. Neonates here may be small for gestational age or have intrauterine growth restriction. Mortality rate in such neonates is 40 times more than neonates with normal weight. Aim of the Work: to investigate the relationship between maternal vitamin D deficiency and low birth weight in Ain Shams University Maternity Hospital. Patients and Methods: our study is a cross-sectional case-control study which conducted at labor ward of Ain Shams Maternity Hospital from February to May 2018, it included 70 term neonate with birth, weight, 35 of them are low birth weight; (normal birth weight: 2500gm-4200gm). Among normal healthy single term pregnant women (37-40 weeks), whose ages vary from 20-35 years old and BMI between 18.5-24.9 kg/m2; after excluding of eclampsia or preeclampsia, DM, polyhydramnios or oligohydramnios, multiple pregnancies, systemic and chronic diseases, anemia (Hgb < 10.5 mg/dl), drug abused or smoking and congenital fetal malformation or infection. Just after delivery, 2 cm of maternal venous blood withdrawn from the 70 pregnant women to make routine complete blood count to exclude anemia, then just after delivery, 2 cm of maternal blood withdrawn to assess maternal 25 Hydroxy vitamin D status using ELISA technique. Results: our study showed the strong relation between maternal vitamin D status during healthy pregnancy and birth outcome birth weight. Results here revealed that maternal hypovitmainosis D is associated with low birth weight of term fetuses, this association was confirmed in many previous studies with different races and populations. Conclusion: Maternal vitamin D level should be measured during pregnancy and any deficiency should be considered to decrease incidence of low birth weight. |