الفهرس 
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Abstract
Epilepsy is a frequent neurological disease in childhood characterized by recurrent seizures and sometimes associated with major effects on social, behavioral and cognitive development that result from abnormal electrical activity in the brain.
Epilepsy is characterized by a long-term risk of recurrent seizures. These seizures may present in several ways depending on the part of the brain involved and the person’s age.
The primary function of the thyroid gland is synthesis of thyroxine (T4) and triiodothyronine (T3). Pituitary thyrotropin regulates thyroid hormone production. Thyroid hormone exerts profound effects on the regulation of gene transcription. Thyroid hormone action include differentiation of the CNS and maintenance of muscle mass. Thyroid hormone also controls skeletal growth and metabolism of carbohydrates, lipids, and vitamins.
Treatment with antiepileptic drugs is associated with multiple short and long term effect on endocrine function, in particular, alteration of thyroid function. Many antiepileptic drugs may alter thyroid hormone hemostasis at the level of biosynthesis, release, transport, metabolism and excretion of thyroid hormone
The aim of the present work is to assess the effect of antiepileptic drugs on thyroid hormones in epileptic patients.
Our study included 120 children aged from 2 years to 10 years old , they were divided as the following.