الفهرس | Only 14 pages are availabe for public view |
Abstract Aim of the study The aim of this study is to evaluate the value of liver function tests ALT and AST in predicting the subsequent development of preeclampsia in high risk women. Conclusion • Liver function tests particularly AST, ALT levels can be used as a potential biomarker for predicting preeclampsia and severity of preeclampsia. • Increased liver enzymes AST and ALT in preeclamptic groups. • The abnormal increase in the levels of liver enzymes in high risk group compared with normal pregnant women suggests that liver dysfunction along with hypertension in early stages of pregnancy can lead to preeclampsia. • The higher levels of the liver enzymes AST and ALT during the first 20 weeks of pregnancy were significantly associated with increased risk for the development of severe preeclampsia during the second half of the pregnancy. Recommendation • There is no clinical cut-off value that can be practically used for the prediction of preeclampsia. Further studies are needed to establish the role of plasma AST and ALT level as predictors of preeclampsia. |