الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 109 |  |  |
| | | from | 109 | | |
Abstract
Endotracheal intubation is a procedure frequently performed in NICUs. In addition to causing pain and discomfort, placing an endotracheal tube (ETT) is associated with systemic and pulmonary hypertension , bradycardia, intracranial hypertension and hypoxia. The bradycardia and hypoxia appear to be independent. Hypoxia can be reduced or avoided by the use of preoxygenation, and by the use of proper laryngoscope blade during the procedure. The bradycardia is vagal in origin, and it is not prevented by preoxygenation and avoidance of hypoxia. The intracranial pressure increase appears to be the result of the coughing and struggling of the infant. According to the current study : Out of those 60 infants, 32 infants were male (53%) and 28 female (47%) with mean gestational age 32.8±2.43 weeks, range between 28 to 36 weeks, and mean birth weight of 1890 ± 451.4 grams, range of 1000 to 2400 grams. Conclusions : from our study we concluded that dexmed is well tolerated in pre term infants and when used as a pre intubation medication it accomplished good intubation condition and had same sedative and analgesic effect as fentanyl Recommendations : We recommend a larger prospective trial upon appropriately powered sample size should be conducted to definitively address the long-term safety and efficacy of dexmed in neonatal field. Also, more researches should be done to identify the value of using dexmed plus muscle relaxants in neonates.