الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
According to the World Health Organization, breast cancer is the most common cancer among women worldwide, with nearly 1.7 million new cases diagnosed in 2012. Breast cancer is the second leading cause of cancer death among women. Breast cancer forms 38.8%of all reported tumors in Egyptian females. Risk factors for developing breast cancer include being female, obesity, lack of physical exercise, drinking alcohol, hormone replacement therapy during menopause, radiation exposure, early age at first menstruation, having children late or not at all, older age, and family history. About 5–10% of cases are due to genes inherited from a person’s parents, including BRCA1 and BRCA2 among others. chronic inflammation as a result of viral infection significantly increases the likelihood of cancer development so inflammation may initiate and promote breast cancer development.To reach our aim we collected blood samples from 139 Egyptian women with breast diseases had mean age 48.7 ± 12.6 years and aged between 25 and 69 years were collected from the Breast Malignancy Database established by the oncology center, Mansoura University, Mansoura, Egypt, and classified into 99 women with breast cancer had mean age = 51.0±11.8 years and aged from 28 to 75 years and 40 women with non-cancerous (benign) had mean age 42.4±11.2 years and aged from 19 to 64 years, in addition, a group of 30 blood samples from healthy women had mean age 45.8 ± 15.3 years and aged from 22 - 67 years were included in the present study as a negative control group.