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العنوان
Evaluation of Fine Needle Aspiration Cytology (FNAC) Role in Diagnosis of Various Breast Lesions and its Diagnostic Pitfalls /
المؤلف
El-Rashedy, Mariam Mahmoud Seleem.
هيئة الاعداد
باحث / Mariam Mahmoud Seleem El-Rashedy
مشرف / Magda Hassan Nasreldin
مشرف / Manal Mohammed El-Mahdy
مناقش / Manal Mohammed El-Mahdy
تاريخ النشر
2017.
عدد الصفحات
205 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض الدم
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - قسم باثولوجيا اكلينيكية
الفهرس
Only 14 pages are availabe for public view

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from 205

Abstract

On studying the role of fine needle aspiration cytology in the diagnosis of various breast lesions, our cross sectional study was carried out on 77 cases representing different breast lesions out of 111 after exclusion who underwent FNAC and biopsies interpretations at Ain shams university hospitals pathology units from 2014 till 2017 with their clinical and radiological assessments.
Correlation between FNAC and biopsy results and the clinical and radiological assessment was done. Benign cases were 47 cases while malignant cases were 30. Most of the patients 98.7% presented by breast lump which was more common on the left side (47%) while rest were either right sided or bilateral. 23.2% were in the clinical grey zone .
Mucious carcinoma was found to be a diagnostic pitfall with benign breast lesion on cytological examination but radiologically it was suspicious. Thus, the diagnostic indices of FNAC were as follow: sensitivity of 96.6%, specificity of 100%, and diagnostic accuracy of 98.7% , and all diagnostic indices reached nearly100% when FNAC incorporated in triple test assessment. The triple test is the recommended approach for the investigation of palpable or impalpable breast lesions detected by imaging. It comprises clinical breast examination and medical history, sono mammography and histopathological assessment like non-excision biopsy , fine needle aspiration cytology and/or core biopsy.
There are more than one method of smear preparation and also stains can be applied either on dry fixed smears or wet smears and this was recorded in our study either by Hematoxylin & eosin stain (46.8%) or Giemsa and Papanicolaou stain(53.2%).
Breast lesions vary widely between benign, inflammatory, atypical, suspicious and frank malignant lesions which has many variants that have their identifying characteristics in cytological specimens and also their common diagnostic pitfalls during the initial diagnosis.