الفهرس 
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Abstract
Nuclear medicine is a branch of medical imaging that uses radioactive tracers (radiopharmaceutical) to assess bodily functions and to diagnose and treat disease. Radioactive tracers are made up of carrier molecules that are bound tightly to a radioactive atom. For most diagnostic studies in nuclear medicine, the radioactive tracer is administered to a patient by intravenous injection. Objective: The present study aims to estimate the role of scintigraphy using captopril in diagnosing renal artery stenosis (RAS) and the abnormalities seen in the renogram curves as well as analytic data including physical parameter((Tmax),T1/2). Methodology: Thirty patients with high suspicious of renal artery stenosis were seen in Urology and Nephrology center at Mansoura University. They were studied at nuclear medicine unit. Two protocol were performed, Captopril scintigraphy was done followed by baseline study five days later. Result: The scintigraphic diagnosis of renovascular hypertension found in nine patients (6 male&3 female) with age ranged between (15&32 years), where parenchymal retention of the tracer was recorded together with prolonged T1/2 and Tmax at captopril study and false negative diagnose in another one. The other twenty cases were negative for RAS because they were normal at captopril study without any parenchymal retention of the tracer. Angiography was done in all suspected ten patients to have RAS and was taken as a gold standard. The criteria which were established for diagnosing Renal artery stenosis result in: there were a discrepancy or marked changes between finding in captopril and baseline studies in the form of prolongation Tmax with (p value =.009) and presence of parenchymal retention of the tracer (prolonged T1/2) at captopril study compared with baseline study. But for negative RAS there is no change in the renogram curve and the parameters of Tmax and T1/2 have a normal values. Also renal scintigraphy using captopril is a good sensitive method of detecting and diagnosing renovascular hypertension functionally.