Search In this Thesis
   Search In this Thesis  
العنوان
Relation between helicobacter pylori and iron deficiency anemia and hepcidin in hemodialysis patients /
المؤلف
Ahmed, Hoda Mohamed Ibrahim.
هيئة الاعداد
باحث / هدي محمد ابراهيم احمد
مشرف / غاده محمد حسن القنيشى
مشرف / دينا عبد الحليم شاهين
مشرف / أحمد عبدالوهاب الجندى
الموضوع
Helicobacter pylori. Internal Medicine. Anemia.
تاريخ النشر
2018.
عدد الصفحات
62 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة المنصورة - كلية الطب - الباطنة العامة
الفهرس
Only 14 pages are availabe for public view

from 86

from 86

Abstract

Anemia develops early in the course of CKD and is nearly universal in patients with ESRD; anemia contributes to poor quality of life in patients with CKD. Fortunately, among the disorders that may affect patients with ESRD, anemia is the most responsive to treatment. Anemia in ESRD patients on hemodialysis mainly due to deficiency of erythropoietin synthesis or iron deficiency, anemia should be evaluated in order to identify any reversible process, the most common reversible cause is iron deficiency. In the general population observational studies have shown a link between H. pylori and iron deficiency, often resulting in iron deficiency anemia. This study was conducted to assess the frequency of H.pylori infection in hemodialysis population and to identify the possible relation between H. pylori infection and iron deficiency anemia in hemodialysis population This study included 84 HD patients randomly selected from dialysis unit in Talkha Central Hospital; it was found that H. pylori stool antigen is positive in 47 patients (group 1, 55.6%), while was negative in 37 patients (group 2, 44.4%). No significant difference was found between infected and non-infected patients regarding hematocrit, hemoglobin, iron, TIBC, ferritin nor TSAT. In the present, there was a significant male predominance in H.pylori infected group. Infection with H.pylori was associated with longer dialysis duration and more dyspeptic symptoms. Infection with H.pylori was associated with high CRP. Hepcidin was higher in the non infected group but no statistical significance was observed. In addition, hepcidin showed no correlation with iron, HB and TSAT. Conclusion: H.pylori was found in 56% of studied patients. Dyspepsia, male sex and HD duration are the strongest predictors of H. pylori in HD patients. Diabetes is less prevalent in infected group. H.pylori infection is associated with higher CRP. H.pylori infection is not related to anemia