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العنوان
ROLE OF PROTON MAGNETIC RESONANCE SPECTROSCOPY IN charACTERIZATION OF INTRACRANIAL LESIONS :
المؤلف
Mohamed, Mahmoud Ibrahim Abo Elnor.
هيئة الاعداد
باحث / محمود ابراهيم ابو النورمحمد
مشرف / محمد السيد الهواري
مناقش / محمدعبد اللطيف محمود
مناقش / محمد احمد سعد
الموضوع
Nervous system.
تاريخ النشر
2016.
عدد الصفحات
157 p. ;
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
2/4/2018
مكان الإجازة
جامعة الفيوم - كلية الطب - الاشعة التشخيصية
الفهرس
Only 14 pages are availabe for public view

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Abstract

Purpose: - is to study the role of MR spectroscopy in characterization of intracranial lesions including differentiation of neoplastic from non-neoplastic lesions as well as grading of malignant lesions.
Subject and methods: - MRS was done for 55 patients having intracranial lesions that could not be characterized definitely based upon conventional MRI sequences, or the clinical presentation (upon clinician point of view) are not matching with imaging findings and so their clinician requested further methods of confirmation, single voxel MRS multivoxel MRS spectroscopy findings were interpreted in addition to the conventional MRI images and results then confirmed based on histopathology findings and/or follow up.
Results: - MR spectroscopy showed 94.1Sensitivity 80.0Specificity 94.1 +ve PV 80.0 -ve PV 90.9Total accuracy in diagnosis of intracranial lesions.
Conclusion: - MRS is proven effective in differentiation of neoplastic from non-neoplastic brain lesions especially necrotic tumors and abscesses as well as in grading of neoplastic lesions and significantly reducing need for stereotactic biopsies.
Key words: - Magnetic resonance imaging, Magnetic resonance spectroscopy, Brain tumors, Gliomas, Cerebral metastasis, Inflammatory brain diseases, Cerebrovascular stroke.