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Abstract Urinary tract infection is one of the most common bacterial infections and gram negative bacteria are among the most prevalent bacteria isolated from UTI patients especially Escherichia coli. uropathogenic E. coli (UPEC) is responsible for 70-95% of community-onset UTIs and approximately 50 % of nosocomial UTIs. The goal of the present work was to detect the presence of extended spectrum beta-lactamase producing Escherichia coli in community-acquired (CA) and hospital-acquired (HA) urinary infections in Tanta University Hospital, to evaluate antimicrobial susceptibility of Escherichia coli isolates and to evaluate different methods for phenotypic confirmation of ESBL producing Escherichia coli. |