الفهرس 
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Abstract
Metabolic syndrome is a clustering of risk factors, such as central obesity, insulin resistance, dyslipidaemia and hypertension that together culminate in the increased risk of type 2 diabetes mellitus and cardiovascular disease. As these conditions are among the leading causes of deaths worldwide.
Vitamin D is a fat-soluble vitamin that is essential for optimal health. It is important for the regulation of calcium and phosphorus absorption, maintenance of healthy bones and teeth, and is suggested to supply a protective effect against multiple diseases and conditions.
Vitamin D deficiency plays key role in the pathophysiology of risk factors of metabolic syndrome which affect cardiovascular system, increase insulin resistance and obesity, stimulate rennin-angiotensin-aldosterone system that cause hypertension. Moreover vitamin D deficiency as well as cardiovascular diseases and related risk factors frequently co-occur.
Metabolic syndrome has a high prevalence in hemodialysis patients and is a risk factor for cardiovascular disease, the leading cause of mortality in chronic kidney disease.
Vitamin D deficiency and insufficiency are common in patients with end-stage renal disease (ESRD) on maintenance hemodialysis. Vitamin D deficiency is associated with increased morbidity and decreased survival in patients with ESRD.
This study aimed to identify the relationship between serum concentrations of vitamin D and metabolic syndrome in hemodialysis patients.
This study was carried out in the hemodialysis unit of Minia University Hospital from July 2016 to July 2017. 90 patients on hemodialysis were included in this study.
All the study subjects were submitted to:
- Thorough clinical history.
- Measurement of weight, height, waist circumference, and blood pressure.
- Laboratory investigations: 25(OH) vitamin D, PTH, lipid profile [total cholesterol, HDL-c, LDL-c, and serum triglycerides], FPG, albumin, total calcium and phosphorus.
The current study revealed that there is a lack of association between serum 25(OH) vitamin D concentrations and metabolic syndrome.
The prevalence of metabolic syndrome as defined by the International Diabetes Federation (IDF) criteria among the hemodialysis patients enrolled in this study was 35.6%.
Reduced HDL-c emerged as the most frequent diagnosed abnormality affecting nearly 67.8% of the enrolled sample.