الفهرس 
Psoriasis
Natural killer T cellsOnly 14 pages are availabe for public view
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Abstract
The pathologic collaboration between innate immunity (mediated by APCs and NK T lymphocytes) and acquired immunity (mediated by T lymphocytes) results in the production of cytokines, chemokines and growth factors that contribute to the inflammatory infiltrate seen in
psoriatic plaques .Narrow-band ultraviolet B (NB-UVB) 113 phototherapy is commonly used in the treatment of Ps, and induction of T-cell apoptosis
has been shown as the main mechanism by which NB-UVB resolves lesions. Clusterin, also known as apolipoprotein J, is encoded on chromosome 8 in humans. It is excreted from various tissues, such as the brain, neural tissue, liver, adrenal glands, and testes. It can be found in serum, cerebrospinal fluid, mother’s milk, semen, and urine. It participates in a number of biological processes, including lipid transport,membrane recycling, cell adhesion, programmed cell death, and complement-mediated cell lysis. Clusterin concentration in HDL strongly and negatively associated with insulin resistance and BMI.Therefore the study aimed to estimate the serum level of clusterin
in psoriatic patients and to study the effect of narrowband ultraviolet B therapy on this level