الفهرس 
Platelet FunctionsOnly 14 pages are availabe for public view
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Abstract
Introduction: Platelets, also called thrombocytes, are a component of blood whose function (along with the coagulation factors) is to stop bleeding by clumping and clogging blood vessel injuries. They play a central role in hemostasis as they contain many hemostatic cofactors and inhibitors in their granules. They also have a role in inflammation since they contain many growth factors.
Aim of the Work: The aim of this essay is to demonstrate the role of antiplatelet agents in treatment of thromboembolic events and to clarify the guidelines for perioperative management of antiplatelet drugs according to case and surgery.
Summary: Platelets are the smallest blood cells, numbering 150 to 400 × 109/L in healthy individuals. The ability of activated platelets to adhere to an injured vessel wall and form aggregates was first described in the 19th century. Besides their long-established roles in thrombosis and hemostasis, platelets are increasingly recognized as pivotal players in numerous other pathophysiological processes including inflammation and atherogenesis, antimicrobial host defense, and tumor growth and metastasis. Consequently, profound knowledge of platelet structure and function is becoming more important in research and in many fields of modern medicine.
Conclusion: Perioperative management of antiplatelet agents is complex, so the team of perioperative clinicians (anesthesiologist, surgeon, and prescribing physician-either neurologist o