الفهرس 
Anatomical considerationOnly 14 pages are availabe for public view
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Abstract
Corneal ulceration leading to perforation can occur secondary to a
number of conditions, including infection, trauma, corneal dryness, and
exposure keratitis. Because the ocular morbidity of corneal perforations is
high, prompt diagnosis and treatment is critical. When persistent corneal
ulceration does not respond to medical treatment, including antibiotics,
therapeutic soft contact lenses, or tarsorrhaphy, surgical intervention is
indicated.
The aim of the work is to maintain the integrity of the anterior chamber
and to control the ocular inflammation.
This study was carried out on 190 eyes of 190 patients suffering from
infectious keratitis with thin cornea about to perforate (clinically
diagnosed).All patients were from those attending Tanta ophthalmology
university hospital from june2014 to june2015.
According to the culture and sensitivity results, the specific
antimicrobial drug was prescribed for each case depending on the highest
organism sensitivity (highest number of positive marks in the culture and
sensitivity report). In this study, an adjunctive treatment to the usual corneal
ulcer treatment including CXL, Cyanoacrylate glue, amniotic membrane
graft& PKP was used. Then patients were followed up at 1 week, 1 month
and 3 months with evaluation of uncorrected visual acuity.
The eyes included in the study were then divided into four groups:
group I included 13 eyes (cyanoacrylate glue), group II included 12 eyes
(CXL), group III included 138 eyes (amniotic membrane graft) and group IV
included 27 eyes (PKP and corneo-scleral graft).