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Abstract Diabetes Mellitus is a disease that affects all tissues and organs of our body. The changes found in the skin are largely parallel to those occurring in the internal organs. Almost all diabetic patients eventually develop skin complications from the long-term effects of diabetes mellitus on the microcirculation and on skin collagen. Complications mainly results from biochemical, structural and functional abnormalities. The present study was carried out on 338 Egyptian patients diagnosed with diabetes mellitus (type 1 or 2) to study the prevalence of different cutaneous disorders among these patients and the relation between these cutaneous manifestations and other variables such as the age and gender of patients, and duration of diabetes. The present study demonstrated that 83.2% of diabetic patients suffered from one or more type of cutaneous disorders. Our results showed that in diabetic patients, cutaneous infections (fungal and bacterial together) were the most prevalent where fungal infections showed the highest prevalence (51.2%) followed by bacterial infections (22%). Acanthosis nigricans was the second disorder (14.2%) followed by cutaneous manifestations of treatment with insulin (11.5%) and diabetic dermopathy (11.3%). Nail dystrophy accounted for (4.4%), followed by thick skin (3.1%), neurotropic ulcers (2.5%) and cutaneous manifestations of oral treatment (2.5%). |