الفهرس 
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Abstract
SUMMARY
Assessment of Female Sexual Function among Women with chronic Dermatological Disease
Introduction:
Skin diseases vary greatly regarding their symptoms, signs, severity, distribution and impact on patients’ lives. In addition to their symptoms and signs; chronic diseases can have detrimental effects on patients’ quality of lives. Diseases of the skin are associated with a negative impact on intimacy (Misery et al., 2007; Arrington et al., 2004), psychological and psychiatric burdens. The sexual dysfuction was strongly associated with psychological impairment; anxiety, depression and suicidal ideation (Sampogna et al, 2017).
Aim of the work
The aim of the current work is to assess the female sexual function among women with chronic dermatological disease.
Patients and Methods
This cross sectional controlled research was designed to study the sexual functions of 100 women suffering from chronic dermatologic disease (group 1) and to compare their sexual functions with that of 100 apparently healthy women (group 2= control group). Included participants answered the 19- item Arabic translation of Female Sexual Function Index (FSFI) questionnaire (Anis et al, 2011) and, for women in group 1, answered the 10-item Arabic translation of Dermatology Life Quality Index (DLQI) questionnaire (Finaly and Khan, 1994).
group 1was sub-grouped into patients with mild, moderate and severe skin disease when it affected < 5%, ≥ 5% but < 20% and ≥20% of body surface area respectively. Furthermore, group 1 was sub-grouped according to the dermatological diagnosis and regarding the presence/absence of skin disease on genitalia and on exposed parts (hand(s), leg(s) face and neck).
Results:
The dermatological diagnosis was: psoriasis (53%), vitiligo (22%), lichen planus (11%), lichen simplex chronicus (9%), discoid lupus (4%) and one case had vitiligo and nail psoriasis. According to the severity of dermatological diseases patients were sub-grouped as: mild (35), moderate (46) and severe (19). Only 46 women had genital region affection and only 70 women had dermatological lesions on exposed parts. The dermatology life quality index (DLQI) score ranged 1.0 – 27.0 (median: 14.0) with a mean 14.19 ± 5.50. The impact of skin disease on the dermatology life quality index (DLQI) was very large in 62 patients, moderate in 18, extremely large in 12 and small in 7; one patient had no effect.
Desire and arousal domains’ scores were significantly lower in patients suffered skin disease (P >0.001 and0.006 respectively) but the total score had insignificant difference (p =0.246). Regarding the presence/absence of female sexual dysfunction: the differences between both groups were statically insignificant using both the international figure (Wiegel et al., 2005) and local figure (Anis et al, 2011) as the P values were 0.396 and 0.141 respectively.
Compared to controls, all the sex domains’ scores and the total score had insignificant differences in the presence of mild dermatological disease
(P > 0.05); all the FSFI scores, excluding the pain domain score, were significantly lower in the presence of severe dermatological disease (P= 0.004 for satisfaction domain’s score but P< 0.001 for all other scores). Desire and arousal domains’ scores were significantly lower (P=0.014 and 0.042 respectively) in the presence of moderate dermatological disease.
In patients with chronic dermatological diseases, all the sex domains’ scores (P < 0.05) and the total score (P = 0.001) were significantly lower in the presence of genital region affection. Arousal (P= 0.008) and satisfaction (p= 0.001) domains’ scores and the total score (p= 0.011) were significantly lower in patients with exposed parts affection.
The type of skin disease had no influence on the female sexual function as indicated by absence of any significant difference between subgroups with different types of skin diseases.
The DLQI score was significantly highest in cases with severe skin disease (P<0.001), significantly higher in presence of skin lesion(s) on genitals and on exposed parts (P< 0.001and P= 0.013 respectively). The type of skin disease insignificantly affected DLQI score (P=0.063).
The duration of the disease was significantly negatively correlated to the satisfaction domain score and was significantly positively correlated to the DLQI score. Apart from the pain domain, DLQI score was significantly positively correlated to all other sex domains scores and to the total score of the FSFI (P < 0.05).
Conclusion
Severe skin disease and/or presence of genital lesions have negative impact on female sexual function.
Moderated skin disease and/or presence of skin lesions on exposed parts can affect some female sexual function domains.
Mild skin disease has no impact on female sexual function.
The kind of skin disease has no influence on female sexual function.
Severe skin disease, genital region affection and exposed part affection can negatively impact quality of life.