الفهرس 
LYMPHATIC SYSTEM
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Abstract
The present study aimed to identify genetic alterations and rearrangements in diffuse large B-cell lymphoma and to examine their association with clinical features, response to therapy and final outcome The study was carried out on 40 subjects of matched age and sex divided into two groups: group (1): included 30 patients with diffuse large B-cell lymphoma. group (2): included 10 normal subjects as a control group. The diagnosis of diffuse large B-cell lymphoma was based on histopathological examination of lymph node and bone marrow biopsies. The patients were further subdivided according to the Ann Arbor staging system into stages (I, II, III and IV). Inclusion criteria:Patient >18 years old with diffuse large B-cell lymphoma. Exclusion criteria: All patients < 18 years old. All patients with other types of lymphoma. All patients with other malignancies. All cases included in the study were subjected to the following: 1- Full history taking. 2- Complete clinical examination including lymph node examination, abdominal, chest and heart examination. 3- Laboratory investigations including: - Complete blood count. Erythrocyte sedimentation rate. Serum lactate dehydrogenase level. Serum.