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العنوان
Dermoscopic criteria of discoid lupus erythematosus /
المؤلف
Awad, Amany Awad Mohamed.
هيئة الاعداد
باحث / أماني عوض محمد عوض
مشرف / حنان فتحي محمد
مشرف / بثينة محروس غانم
مشرف / شرين رفعت محمد
مناقش / سامية علي إبراهيم
مناقش / عبير محمد عبدالعزيز الخولي
الموضوع
Dermatology. Skin Neoplasms. Skin - Diseases.
تاريخ النشر
2018.
عدد الصفحات
144 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأمراض الجلدية
تاريخ الإجازة
01/09/2018
مكان الإجازة
جامعة المنصورة - كلية الطب - Dermatology
الفهرس
Only 14 pages are availabe for public view

from 144

from 144

Abstract

A high percent of patients have disease located on the head and neck (localized DLE), but a lower percent have much more extensive disease, affecting any site of the skin (disseminated DLE) (Ribero et al., 2016). The face and scalp are more frequently affected in localized disease specially the cheeks, bridge of the nose, ears, side of the neck and scalp (Siah and Shapiro 2015) as well-defined erythematous patches, of different sizes from a few millimetres to 10–15 cm. Adherent scale may be present which upon its removal, show horny plugs on its undersurface that have occupied dilated pilosebaceous openings that is termed ‘tin‐tack’ sign. The surface may present a dirty, brownish yellow appearance that is rough to the touch because of follicular plugging. Scarring alopecia occurs in the scalp lesions in approximately one-third of patients and is usually permanent (Wenzel 2015). DLE may be in a widespread pattern on the trunk and limbs, or may be localized to other areas. This is more frequent in women who are usually cigarette smokers. The presentation may be very similar to the papulosquamous type of SCLE but with more scarring. This type is more persistent, resistant to therapy and results in severe psychological disturbance. Dorsa of the hands, palms or toes may be affected. Purple plaques may affect the front of the knees and the back of the heels (Kuhn and Landmann 2014). Summary and Conclusion This study shows that whitish scales, arborizing blood vessels, follicular plugging and pigmentation are the most frequent dermoscopic findings of DLE lesions. Perifollicular whitish halo, white structureless areas, follicular red dots, Rosettes and Radial arrangement of arborizing blood vessel around radially arranged perifollicular whitish halo were also noticed in this study. Our results confirm the non-specificity of the rosettes in diagnosis of any skin disease just an optical effect of crossed polarization. Radial arrangement of arborizing blood vessel around radially arranged perifollicular whitish halo reported for the first time in this study and appears in early stages of the DLE lesions and more frequent in lesions outside scalp area. This study shows that there is a good agreement between many of the dermoscopic and pathological findings as follicular plugging and follicular hyperkeratosis, telangectasia and dilated dermal blood vessels also follicular red dots and perifollicular extravasation of red blood cells. We found a high sensitivity of follicular plugging (95.8%), arborizing blood vessels (95.8%), scales (95.2%), pigmentation (95.5%) and follicular red dots (90%) and high specificity of follicular plugging (100%).