الفهرس 
Soft tissue sarcoma
Relative contraindications to limb-sparing proceduresOnly 14 pages are availabe for public view
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Abstract
Background: Skeletal and extra-skeletal sarcomas are increasingly common nowadays. the tumor being in the lower extremity increases the morbidity and disturbs patient’s quality of life even more. In this study, we are addressing the outcomes of vascular reconstruction in limb salvage for management of lower extremity sarcomas.
Methods: This systematic review consisted of 4 steps, including a systematic search of the literature (PubMed, SCOPUS, Web of Science, and The Cochrane Library), selection of studies, recording of study characteristics. and extraction of data on clinical outcomes and their comparisons between different surgical groups.
Results: A total of 54 studies were identified and 18 were included in the meta-analysis. Quality assessment indicated that only three studies were of high quality. The mean age of the participants ranged from 12 to 56 years, the mean length of follow-up ranged from 28 to 145 months. The meta-analysis indicated that the oncological outcomes and survival were similar between patients who underwent vascular reconstruction and those who underwent a limb-salvage procedure without vascular reconstruction.
Conclusion: Limb salvage with vascular reconstruction in lower extremity sarcomas is a viable and safe option to avoid limb amputation. yet further high quality randomized studies are required to support the conclusion of this study.