الفهرس 
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Abstract
A total of 4344 blood samples were collected from 3214 Dairy cows and 1130 from buffaloes were examined serologically by RBPT, TAT, BAPAT and RiV.teses.
In cows. Positive cases in different Ismailia localities were -232(7.2) for Rose Bengal Plate test. -190(5.9%) for Tube agglutination test. -178(5.5%) for Buffered acidified Plate test. -182(5.7) for Rivanol test. In Buffaloes. Positive cases in different Ismailia localities were -42 (3.7) for Rose Bengal Plate test. -34 (3%) for Tube agglutination test. -29 (2.7 %) for Buffered acidified Plate test. -31 (2.9) for Rivanol test. 500 Blood samples were collected from Inpatients in Suez Canal University Hospitals and fever hospitals of Ismailia, and 170 blood samples were collected from Outpatients group as well as 56 blood samples from farm workers. Positive result in RBPT(10.6%), (5.8%)by TATab.ag ,(5,6%) by TAT m.ag ,(7,3%) by BAPAT and (7,7) by Riv .T. Age from 20-40 years more affected by brucellosis .Number of positive in male(68,8%) and Female(31,2%). Milk samples were collected from dairy animals 260 from cows and 80 from buffaloes) for milk ring test.130 cows and 25 from buffaloes are reacted by MRT.
Result of heamogram in animal revealed The results revealed high significant decrease in RBCs count, Hb concentration and PCV% with significant decrease in MCHC and increase MCV resulting in normocytic hypochromic anaemia in comparison with control group. highly significant increase in Total leucocytic count in brucella serologically positive cows compared with control group. Neutrophil and Monocyte counts were found higher than the standard values. On the other hand highly significant decrease in Lymphocyte. patients with brucellosis the anaemia . A normal or reduced leucocyte count and thrombocytopenia. Serum biochemical studies revealed in the diseased dairy cattle and man with brucellosis , (ALT), (AST) and (AP) showed a significant increase when compared with the healthy groups. highly significant decrease in the total protein and albumin, and a significant increase in the globulin when compared with control group. a highly significant decrease in calcium and inorganic phosphorus, magnesium and sodium. there was non significant changes of thyroid function tests 0f brucellosis in human and animals.
Histopathological examination of Liver showed subacute hepatitis represented by hyperemia of hepatic and portal blood vessels ,leukocytic infiltration and edema. The uterus showed chronic metrits includes endometritis myomerits and perimetrits. The endometrial changes were thickening of lamina propria and submucosal, Leukocytic infiltration, fibrosis and cystic dilatation of endometrial glands. myometrial degeneration. mild leukocytic infiltration and calcification were.