الفهرس 
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Abstract
A variety of factors were proposed to be implicated in the maturity onset of cataract genesis including low antioxidant defense capacity, high lipid peroxidation, an augmented non enzymatic glycosylation, a reduced chaperone function of the alpha crystalline and an increased permeability of the lens membrane. Researchers have shown that the oxidative stress which is caused due to the accumulation of free radicals plays a role in the pathogenesis of cataracts and that this process can be prevented or ameliorated by antioxidants.
So, the present study aimed to evaluate the role of oxidative stress in cataract patients. The study included 30 patients in addition to age and sex matched 30 healthy controls. All participants were subjected to careful history taking, thorough clinical examination and laboratory examination including assessment of MDA, IMA, catalase and SOD in serum, aqueous and lens of the studied patients
In our study, patients were found to have significantly higher MDA and IMA levels when compared to controls. They were also found to have significantly lower levels of catalase and SOD when compared to controls.
Analytical study of the relation between the various oxidative stress markers and the various clinical data revealed the studied patients showed significant direct correlation between patients age and serum MDA levels. However, no statistically significant relations were noted between oxidative markers and patients gender. Also, we found no statistically significant differences between cataract types regarding oxidative stress markers levels