الفهرس 
Reproductive and Hormonal Factorsيوجد فقط 14 صفحة متاحة للعرض العام
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المستخلص
Cancer development involves conversion of normal cells to malignant cancer cells through the generation of genetic, epigenetic and other changes, so-called ‘multi-step carcinogenesis. Quercetin (3,3’,4’,5,7-pentahydroxyflavone) seems to be the most powerful flavonoids for protecting the body against reactive oxygen species, produced during the normal oxygen metabolism or are induced by exogenous damage. Methotrexate (MTX) (brand name Methoblastin) is an antifolate drug that is used inthe treatment of cancer, autoimmune diseases and in induction of medical abortion. MTX competitively inhibits dihydrofolate reductase (DHFR), an enzyme that catalyses the conversion of dihydrofolate to the active tetrahydrofolate. Folic acid is needed for DNA synthesis. The aim of the current study was to evaluate the anti-tumor potential of Quercetin.