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Abstract Hepatitis C virus (HCV) is a serious health problem worldwide that causes chronic infection in up to 85% of cases and can later progress to active liver disease, liver failure, or primary hepatocellular carcinoma. Egypt has the highest prevalence of HCV infection where 14.9 % of Egyptian populations are anti- HCV positive. The effectiveness of the current therapy for HCV (pegylated interferon-α/ribavirin) combination ranges from 45-65%. In addition, it is very costly with many serious adverse effects. |