الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Pre-eclampsia (PE), a syndrome of pregnant women, is one of the most important complications for pregnancy. It complicates 5-7% of all pregnant women and about 10-12% of all primigravida. It is the most common cause of maternal and fetal morbidity and mortality. In preeclampsia, there is development of hypertension and proteinuria after 20 weeks of gestation in a previously normotensive, non-proteinuric pregnant women .
Placental growth factor is a 45 to 50 kDa dimeric glycoprotein and it is a vascular endothelial growth factor homologue that also has angiogenic potential. It is produced and secreted by placental tissue and endothelial cells. PLGF induces angiogenesis both directily as well as by amplifying the effect of VEGF.