الفهرس 
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Abstract
Dematological problems are reported to be the most commonly encountered and can be a nightmare for the unfortunate and frustrating for the veterinarians and dog owners in small animal practice. The present study was carried out on a total number of 65 dogs with different breeds, sexes and ages divided into 3 groups: 10 cases apparently healthy, 43 diseased dogs and 12 cases for therapeutic trial. The result of epidemiological analysis showed that the highest percentage of canine pyoderma was found in age ranging from 1-3y), in German Shepherd breed and females were more susceptible than males , Prevalence of G+ve and G-ve Pyoderma were 86 % and 14% respectively, Clinical and microscopical examination revealed 11 cases of primary idiopathic pyoderma, 32 cases of secondary pyoderma due to different etiologies (24 cases of demodicosis and 8 cases of FAD). The main clinical signs recorded with canine pyoderma were severe pruritus, erythema, cracks, excoriations, and papules, pustules, marked alopecia, epidermal collarettes, furuncles, bad odor of skin and easily epilated hair were observed in all examined dogs, Clinical improvement was observed in all cases after treatment by 2- 3 weeks. The result of The bacteriological and molecular aspect of canine pyoderma showed that staphylococci especially S.aureus were the most common cause of canine pyoderma , Concerning antibiotic sensitivity The isolated staphylococci showed a high sensitivity to Amoxicillin+ clavulinic acid (43.2%), while The G-ve Pyoderma were sensitive to Neomycin (50%). The result of the hematological profile of canine pyoderma in G+ve pyoderma cases showed normocytic normochromic anemia. The result of therapeutic trial showed four samples of G+ve pyoderma from 5 Staphylococci samples were positive for MRSA. It denoted 2 cases of G+ve pyoderma patient which not respond to cefopodoxime-Clavulinic acid, suggested that cefpodoxime with clavulanic acid is safe and effective in the treatment of recurrent superficial and recurrent deep pyoderma in dogs.