الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Sepsis is a major cause of intensive care unit admission and is associated with high morbidity and mortality rates. Pre PICU management in cases of severe sepsis and septic shock remains an extremely important factor in the outcome of the patients, and it can also be the direct cause of better outcome of cases
Severe sepsis and septic shock are medical emergency conditions that should alert any staff member working in the health care system at any level, and be treated with the highest priority in patient care. “The golden hour”, the time period within which rapid treatment can make an outcome difference between life and death, is nowadays a well-known term to describe the fact that within an hour the clinician has a good chance to reduce mortality and also morbidity (“time is organ”). Early recognition and treatment of sepsis can be life-saving for children in developed and pre-developed countries.
The aim of this study was to find a correlation between the pre PICU management and the outcome in pediatric patients with severe sepsis and septic shock.
The current study was carried on 40 pediatric patients aged from 1 month to 144 months of both sexes with the diagnosis of severe sepsis or septic shock admitted to the Pediatric Intensive Care Unit in Alexandria University Children’s Hospital.
The history was taken and clinical condition of the patients on admission was evaluated using pediatric index of mortality (PIM2) score and daily follow up using the Laboratory investigations were recorded.
The cases were divided according to fate into 2 groups, survivor group (19 patients) and non-survivor group (21 patients).
In this study we found no significant difference between survivors and non survivors as regarding to demographic characteristics, type of antibiotic, clinical source of sepsis, CRP and WBC.