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Abstract Introduction: Breast cancer is the most common cancer among women, accounting for 29% of newly diagnosed cancers, and is the second most common cause of death from cancer in women. Digital breast tomosynthesis (DBT) is a newly developed form of three dimensional (3D) imaging with the potential to improve the accuracy of mammography by reducing tissue overlap. Aim of the Work: To highlight the role of Digital breast tomosynthesis (DBT) in evaluation of breast lesions. Summary: It was demonstrated that the addition of tomosynthesis to 2D imaging provides improved performance in both fatty and dense breasts, compared to 2D alone, with the performance gain in dense breasts higher than in fatty breasts. Contrast-enhanced DBT can be used to facilitate three dimensional images of contrast agent distribution through the breast tissue so help in detection of breast cancer, so reducing the cost and the contraindications of the breast MRI. Conclusion: DBT has many advantages over mammography as; reducing challenges due to overlapping structures in breast tissue associated with two-dimensional mammography, increases lesion and margin visibility and helps to localize structures in the breast, all of which leads to increased cancer detection and reduced false-positive recalls, also DBT is found to improve sensitivity, specificity and the accuracy of the lesion size measurement in women with dense breast. |