الفهرس 
Principles of DWIOnly 14 pages are availabe for public view
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Abstract
There is growing interest in the applications of diffusion-weighted-imaging (DWI) in oncologic area. DWI has important advantages because it does not require contrast medium, is very quick technique and it provides qualitative and quantitative information that can be helpful for tumor assessment.
DWI is an imaging technique which provides tissue contrast by the measurement of diffusion properties of water molecules within tissues. Diffusion is expressed in an apparent diffusion coefficient (ADC), which reflects the diffusion properties unique to each type of tissue.
Both low and high b-value DWI are effective in suppressing vascular structures that may mimic or obscure liver lesions, but low b-value DWI provides a higher signal-to-noise ratio, is less prone to cardiac motion-induced signal loss, and suffers less from eddy current-induced distortions. Previous studies have already shown that low b-value DWI is more sensitive than high b-value DWI in detecting malignant liver lesions
Materials and Methods
Twenty patients were included in this study. The cases were evaluated over 6 month’s duration at Ain Shams University Hospital with a 1.5 Tesla Phillips (MR System Achieva) whole body imager.
RESULTS
Twenty patients were included in this study. The cases were evaluated over 6 month’s duration at Ain Shams University Hospital with a 1.5 Tesla Phillips (MR System Achieva) whole body imager using a body phased array synergy coil.
Diagnostic Performance of metastasis in DWI Discrimination of true number of metastasis.
Sen. Spe. PPV NPV Accuracy
100.0% 90.0% 90.9% 100.0% 95%
CONCLUSION
DWI alone has high sensitivity and specificity so in cases where gadolinium injection is not allowed, dynamic contrast-enhanced imaging can be replaced by a protocol based on unenhanced T1- and T2-weighted imaging combined with DWI.