الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 190 |  |  |
| | | from | 190 | | |
Abstract
This study was carried out to evaluate the effectiveness of platelet rich fibrin (PRF) on healing of hard and soft tissues in peri-implant defects after immediate implant placement. This study was conducted on 10 adult patients with an age range of 20 to 50 years having remaining roots of single rooted teeth indicated for extraction. They were selected from the Out-Patient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University.
The patients were divided into two groups
• Study group: Composed of 5 patients in need for extraction of single rooted tooth (width of the socket at the coronal third > 2mm), underwent immediate implant placement with PRF combined with allogenic bone graft.
• Control group: Composed of 5 patients in need for extraction of single rooted tooth (width of the socket at the coronal third > 2mm); underwent immediate implant placement with bone graft. Without PRF.
Postoperative antibiotic and analgesics were prescribed. All patients were advised to maintain Proper oral hygiene by using warm antiseptic mouth wash starting on the second post-operative day and lasting for a week. The sutures were removed after 7 days.
The post-operative evaluation was performed both clinically and radiographically.
Clinical evaluation
The study was performed to evaluate:
• Pain: using the visual analogue scale on the second day, after 45 days and after 3 months.
• Edema: on the second postoperative pain.
• Modified sulcus bleeding index (MSBI): using criteria of MSBI by Mombelli et al. after 6 months.
• Peri-implant probing depth: after 6 months.
Implant stability
Stability of all implants was determined at base line and 6 months later using osstell.
Radiographic evaluation
To evaluate:
1- Bone density and oseointegration around implants.
2- Marginal bone level.
Digital periapical radiographs were taken preoperative, immediate postoperative, after 3 and 6 months.
The digital radiographic imaging was analyzed with the aid of x-ray analysis software: Image J software.
This study showed less pain in the study group than in the control group on the second post operative day but the difference was not significant.
Post-operative edema was also less pronounced in the study group than in the control group on the second postoperative day, although the difference was not significant.
There was decrease in the probing depth and bleeding index in the study group than in the control group on the 6th postoperative month, although the difference was not significant.
Also, there was significant increase in bone density and significant decrease in marginal bone loss in the study group than in the control group on the sixth postoperative month.
from this study, it is clear that PRF is considered a good material for bone fill and therapeutic agent of choice in the treatment of bone defect sites.