الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Acute pain management is an important aspect of perioperative anesthetic care. Inadequate postoperative analgesia has been shown to contribute to adverse outcomes including, but not limited to, immuno-suppression, hyperglycemia, poor rehabilitation, and progression to chronic pain.
This study compared the intraoperative haemodynamics and postoperative recovery profile and analgesia while using ketamine versus fentanyl infusion in patients undergoing spine surgery.
The present study was performed on 60 adult patients aged 18-60 years old from American society of Anesthesiology (ASA) physical status I-II scheduled for elective spine surgery under general anesthesia were allocated into two groups 30 patients each. Anesthesia was maintained intraoperative and postoperation for 24 hours with ketamine infusion (0.02-0.2 mg/kg/hour) in group A and – fentanyl infusion (1-2mcg/kg/hour) in group B .
It is found that Low-dose ketamine infusion is more effective in postoperative pain management after spine surgery than fentanyl infusion. It maintains intraoperative hemodynamic stability and provides postoperative analgesia. It decreases incidence of complications associated with the use of opioids infusion as it decreases PONV, length of stay in the hospital. It also reduces the requirement for postoperative analgesia in patients undergoing any spine surgery.