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Abstract Neonatal septicemia is one of the major health problems throughout the world. Despite improved neonatal care over the past decades, infections remain common and sometimes life-threatening in neonates admitted to the neonatal intensive care unit (NICU). Despite the application of modern antibiotics and resuscitation therapies, the mortality of septic patients remains high, especially in those with severe sepsis. In the United States, severe sepsis accounts for 751,000 hospital admissions and 215,000 deaths every year, the mortality is up to 28.6%. Several maternal risk factors have been identified that are associated with incidence of neonatal sepsis such as premature onset of labour, prolonged premature rupture of fetal membranes, chorioamnionitis and UTI. |