الفهرس | Only 14 pages are availabe for public view |
Abstract In our study, ALT was significantly highest in NASH group, followed by NAFLD and lowest in control group with no significant difference between control and NAFLD groups. But, there was no significant difference between study groups regarding AST. Our study showed that retinoic acid was significantly different among studied groups, was lowest in NASH group, followed by NAFLD and high in control group. Also, NAFLD score was significantly highest in NASH group, followed by NAFLD and lowest in control group with no significant difference between control and NAFLD groups. NAFLD grade was significantly different among study groups; was highest in NASH group, followed by NAFLD and lowest in control group. Correlations revealed significant negative correlations between retinoic acid and NAFLD score among NAFLD and NASH groups. Receiver operating characteristics (ROC) curve was used to define the best cutoff value of serum retinoic acid level. Retinoic acid had significantly high diagnostic performance in differentiation between NAFLD group and control group with 80% sensitivity and 100% specificity and also in differentiation between NASH group and NAFLD group with 82.5% sensitivity and 77.5% specificity. |