![]() | Only 14 pages are availabe for public view |
Abstract Background: Diabetes mellitus is encountered as one of the most challenging health care problems in the 21st century and its prevalence is higher in developing countries. While for year 2030, 170% increase is expected for developing countries, 42% expected for developed countries. Diabetic peripheral neuropathy (DPN) is a common complication in patients with diabetes, and it affects more than 30% of patients with type2 diabetes mellitus. Several studies demonstrated that, when controlled for confounding factors such as age, gender, BMI, renal function, and/or diabetic duration, SUA levels were high in patients with diabetic polyneuropathy and sudomotor dysfunction Aim of the Study: The aim of this study is to investigate the association of serum uric acid and diabetic peripheral neuropathy in type 2 diabetic patients. Patients and Methods: This study is a case control study; was conducted on 60 patients with type 2 diabetes aged between 45-59 years. Patient were divided to two groups group A: Thirty patients with type 2 diabetes has peripheral neuropathy proved by nerve conduction test and matched as regard to age, gender, BMI, renal function as case group. group B: Thirty patients with type 2 diabetes mellitus has no peripheral neuropathy proved by nerve conduction test and matched as regard to age, gender, BMI, renal function as control group. Results: It was found that there is statistically highly significance difference between group A (4.86±0.71) versus group B (3.78±0.8) P. value <0.001.it was found that there is positive relation between serum uric acid and DPN. As serum uric acid is significantly higher in patients with DPN Conclusion: The results show the higher level of serum uric acid level in type 2 diabetic patients with diabetic neuropathy. |