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العنوان
Role of Intact Parathyroid Hormone Level as an Early Predictor of Postoperative Hypocalcemia after Total Thyroidectomy for Simple Multi-Nodular Goiter/
المؤلف
Mahmoud,Rana Mahmoud Abdoh .
هيئة الاعداد
باحث / رنا محمود عبده محمود
مشرف / أيمن عبد الله عبد ربه
مشرف / أحمد محمد كمال
مشرف / عمرو حامد عفيفي
تاريخ النشر
2017.
عدد الصفحات
169.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة
تاريخ الإجازة
1/10/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - General Surgery
الفهرس
Only 14 pages are availabe for public view

from 169

from 169

Abstract

Serum PTH 24-h after total thyroidectomy is a reliable predictor of hypocalcaemia and can allow safe early discharge of patients from hospital. Patients with a normal postoperative serum PTH and normal serum calcium the following morning will not develop hypocalcaemia and can be considered for discharge that day. Measuring %iPTH decline, where a decline >72.3% was precise for early diagnosis of hypocalcemia after total thyroidectomy too. Our study didn’t find a difference, between combination of both tests and measuring iPTH24hr only, also did not increase the accuracy. Thus, calculation of the %iPTH decline might not be necessary. Only using a single measurement of iPTH24hr is more convenient and cost-effective in early diagnosis of immediate significant postoperative hypocalcemia.
This is a prospective study to estimate the incidence of hypocalcemia and hypo-parathyroidism following total thyroidectomy for simple multi-nodular goiter (SMNG), and to determine which early clinical and biochemical characteristics could be considered as predictive factors. Also to identify PTH-24 (iPTH-24hr) as a simple predictor of early postoperative hypocalcemia.