الفهرس 
Osteoarthritis in ElderlyOnly 14 pages are availabe for public view
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Abstract
Introduction: Osteoarthritis (OA) is the most common form of arthritis. It is among the most prevalent and disabling chronic conditions worldwide. It is predicted to be the single greatest cause of disability in the general population by 2030. The prevalence increases with age, and by the age of 65, approximately 80 percent of the population is affected. Nearly 60% of populations with arthritis are women.
Aim of the Work: This study was conducted in order to assess gender difference response to platelets rich plasma intra articular injections in patients with knee osteoarthritis.
Patients and Methods: One arm clinical trial was conducted to study the efficacy of PRP injections in elderly and to assess gender difference response to PRP intra articular injections in elderly patients with knee osteoarthritis.
In this study about 250 patients attended outpatient clinics and inpatients wards of Ain Shams University Hospital were examined and the diagnosis of bilateral knee osteoarthritis disease was established. Among those patients a sample of 44 patients (22 females and 22 males) fulfilling inclusion and exclusion criteria in our study was randomly selected by simple random sampling to participate in the study.
Results: The study sample comprised 44 elderly participants aged sixty years and above with mild to moderate knee osteoarthritis according to Kellgren-Lawrence Grading Scale: (Kellegren and Lawrence, 1957). The studied sample was divided into two equal matched age groups:
group A: 22 male patients 60 years old and above with knee osteoarthritis.
group B: 22 female patients 60 years old and above with knee osteoarthritis
Conclusion: Intra-articular injection of PRP in knee OA may be a valid alternative treatment for knee osteoarthritis.
Recommendations: PRP intraarticular therapy should be considered as an alternative therapy in management of knee OA among the elderly. Radiographic imaging assessment should be included to evaluate OA progression and provide objective data on clinical improvement of cartilage quality.