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العنوان
Assessment of Decidual Natural Killer Cells CD56+ Population in Placental Bed in Fetal Growth Restriction/
المؤلف
Kasim,Noha Mahmoud .
هيئة الاعداد
باحث / نهى محمود قاسم
مشرف / محمد علاء محي الدين الغنام
مشرف / محمد المندوه محمد
مشرف / محمد سعيد الدين الصفتي
تاريخ النشر
2017.
عدد الصفحات
140.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/10/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - Obstetrics and Gynecology
الفهرس
Only 14 pages are availabe for public view

from 139

from 139

Abstract

Aim: this study to compare the density of decidual natural killer cells (CD56) in deciduas of placental bed in patients with Intrauterine Growth Retardation (IUGR) and women with normal pregnancy.
Patients and Methods: in the study 23 pregnant women were recruited and divided into 2 groups: The study group (A): included 14 patient females which diagnosed as IUGR by ultrasound of the third trimester and the control group (B): included 14 normal females at third trimester with no antenatal complications recruited from the antenatal care clinics. All patients underwent elective cesarean delivery. Decidual biopsies were taken during the operation. An immunohistochemical staining for decidual natural killer cells (dNK, CD56+bright) and a semi quantitative scoring were done.
Results: In this study it was found that the Immunohistochemical scores and dNK cell population density is statistically higher in controls compare with IUGR group (P<0.01)
Conclusions: findings reinforce the concept of pregnancy as a controlled systemic inflammatory state that if altered can have adverse consequences for the mother and the fetus.