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Abstract Cases had higher incidence of dyslipidemia, poor glycemic control, in compare to control However control group had high incidence of MI as macrovascular complication in compare to cases. Duration of diabetes wasn’t associated with increased risk of MCI. A-MCI is more predominant than NA-MCI among elderly diabetics with MCI. The accuracy of salivary Aβ42 to detect MCI, at cut off >47.5 pg /ml, was moderate with AUC= 0.65, with sensitivity 80 %, specificity47% PPV 60%, NPV 70 %. Family history of memory impairment is associated with increased risk of MCI. The level of salivary Aβ42 was significantly higher in MCI than controls and was significant predictor of MCI with and without adjustment of vascular risk factors. Apart from the significant vascular risk factors, salivary amyloid was a significant predictor of MCI in diabetics. A-MCI is more predominant than NA-MCI among elderly diabetics with MCI |