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العنوان
MALIGNANT BREAST TUMOURS: ROLE OF MRI IN PREDICTING HISTOPATHOLOGICAL GRADING/
المؤلف
Hasan,Zinah Nashee .
هيئة الاعداد
باحث / زينه ناشي حسن
مشرف / حسام مــوســي صــقر
مشرف / عـلام السيد عـلام
تاريخ النشر
2017.
عدد الصفحات
146.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/8/2017
مكان الإجازة
جامعة عين شمس - كلية الطب - Radiodiagnosis
الفهرس
Only 14 pages are availabe for public view

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from 146

Abstract

Introduction: Magnetic Resonance Imaging (MRI) is an established supplemental technique to mammography and ultrasonography for evaluation of breast lesions. DWI is quantified using the Apparent Diffusion Coefficient (ADC) value which is the measurement of the mean diffusivity of water in tissues along three orthogonal directions.
Aim of the Work: The aim of this study is to investigate the relationship between DWI findings (represented by ADC values) and the dynamic contrast enhanced MRI findings (including functional parameters and morphological criteria) with the histopathological grade of malignant breast tumours.
Patients and Methods: 25 patients (age >30 years) were enrolled in this study. All patients were referred either from the screening clinic or the outpatient clinic of Eldemerdash Hospital with clinically suspicious findings and the abnormality was detected by mammography and/or ultrasound.
Results: Twenty five female patients were included in this study, their age > 30 years. Histopathological analysis revealed all 25 lesions to be invasive ductal carcinomas not otherwise specified. Grading of included carcinomas was as follows: 3 lesions (12.0%) were grade I, 14 lesions (56.0%) were grade II and 8 lesions (32.0%) were grade III.
Conclusion: That makes DWI the best non-invasive tool available to predict grades of breast carcinoma.
However, further larger and more detailed studies are still needed to fully understand the role MR imaging in distinguishing different histological grades of breast cancer.